As the 2025 NFL season reaches Week 10, injuries continue to play a pivotal role in shaping the outcomes of games across the league. With the regular season entering its final stretch, teams are grappling with key players sidelined or questionable, impacting lineups and game plans. This week’s injury reports reveal a mix of significant absences and encouraging returns ahead of Sunday’s games, as well as Monday Night Football’s marquee matchup between the Green Bay Packers and the Philadelphia Eagles. Here’s a detailed look at the latest injury updates and their potential implications for Week 10 action.
### Quarterback and Skill Position Injuries
One of the headline injury developments involves Houston Texans quarterback C.J. Stroud, who has been ruled out for Sunday’s game due to a concussion. Stroud’s absence means veteran Davis Mills will take the helm under center, a crucial adjustment for the Texans as they face a challenging opponent. On the brighter side for the Carolina Panthers, star running back Rico Dowdle has been upgraded to “good to go” after progressing from limited practice earlier in the week to full participation on Friday. Dowdle is expected to be a key offensive weapon against the New Orleans Saints, providing the Panthers with a much-needed boost in their ground game.
The Philadelphia Eagles enter their Monday Night Football matchup relatively healthy, with only cornerback Adoree’ Jackson and center Cam Jurgens missing Friday’s practice due to a personal matter/concussion and knee issue, respectively. Meanwhile, the Green Bay Packers are managing a few concerns heading into the big game, as edge rusher Lukas Van Ness (foot) and cornerback Nate Hobbs (knee) missed practice on both Thursday and Friday. Rookie wide receiver Matthew Golden also did not practice Friday after limited participation on Thursday, leaving his status uncertain.
### Defensive Injuries Impacting Key Units
Several teams are facing significant defensive injuries that could alter their effectiveness on the field. The Indianapolis Colts, for example, have placed three-time Pro Bowl defensive tackle DeForest Buckner on injured reserve due to a neck injury, sidelining him for at least four games. Additionally, defensive ends Samson Ebukam (knee) and Tyquan Lewis (groin) are ruled out for Sunday, leaving the Colts shorthanded along the defensive line. However, All-Pro cornerback Sauce Gardner is expected to make his Indianapolis debut on Sunday after fully practicing all week, a welcome return that could help stabilize the Colts’ secondary.
The Buffalo Bills have ruled out defensive end A.J. Epenesa (concussion) and linebacker Shaq Thompson (hamstring), both of whom did not practice all week. Corners Taron Johnson (groin), defensive tackle DaQuan Jones (calf), and receiver Joshua Palmer (knee, ankle) remain questionable after limited practices midweek. Similarly, the Miami Dolphins face defensive challenges with corner Rasul Douglas (foot, ankle) and edge rusher Chop Robinson (concussion) both doubtful after limited or no practice. Safety Ifeatu Melifonwu (thumb, foot) and safety Ashtyn Davis (quad) are questionable, though they saw limited practice time during the week.
### Offensive Line and Skill Position Concerns
Injuries along the offensive line and to skill players continue to affect several teams’ offensive strategies. The Atlanta Falcons will be without key contributors including edge rusher Leonard Floyd (hamstring), offensive linemen Matthew Bergeron (ankle) and Storm Norton (foot), all of whom did not practice during the week. Cornerback Mike Hughes (neck) remains questionable after limited practice participation.
The Jacksonville Jaguars have several offensive players ruled out, including wide receiver Brian Thomas Jr., tight end Hunter Long (hip, knee), corner Jourdan Lewis (neck), and offensive lineman Ezra Cleveland (knee, ankle). These absences elevate newly acquired wide receiver Jakobi Meyers to the team’s top target, especially with Travis Hunter still on injured reserve.
Cleveland Browns wide receiver Isaiah Bond (foot) is ruled out, while linebacker Carson Schwesinger (ankle), wide receiver Cedric Tillman (hamstring), tight end Harold Fannin Jr. (hamstring), and offensive tackle Cornelius Lucas (back) are all questionable after varying degrees of practice participation.
The New Orleans Saints will be without offensive tackle Taliese Fuaga (ankle), who did not practice all week. Running back Alvin Kamara (ankle) and tight end Jack